New Heights

Hsp90 reaches new heights

Introduction Hsp90 (heat-shock protein 90) is an abundant molecular chaperone, but its function seems to be restricted to the folding of proteins involved in cell signalling, such as transcription factors and protein kinases. This restricted set of ‘clients’ (see Fig. 1) makes Hsp90 an attractive target for cancer therapeutics. As an anti-Hsp90 drug is now in clinical trials, the meeting was re...

Peripheral blood stem cells reach new heights.

Indian Banking-Scaling New Heights in Emerging New Competition

Indian banking industry has transformed in recent years due to the globalization market which has resulted in fierce competition. This new competitive environment has resulted in new challenges for the Indian banks especially for public sector banks to retain their share. The present paper is mainly concerned with the analysis of factors that influence the performance of banks. The paper examin...

Intersecting Word Vectors to Take Figurative Language to New Heights

This paper proposes a technique to create figurative relationships using Mikolov et al.’s word vectors. Drawing on existing work on figurative language, we start with a pair of words and use the intersection of word vector similarity sets to blend the distinct semantic spaces of the two words. We conduct preliminary quantitative and qualitative observations to compare the use of this novel inte...

Taking Neural Crest Stem Cells to New Heights

The carotid body is an organ of the peripheral nervous system that senses oxygen concentration in the blood and responds to changes by regulating breathing. Pardal et al. (2007) now report the discovery of carotid body stem cells, which proliferate in response to hypoxia and generate neurons that secrete dopamine. This new source of adult stem cells may be useful in therapies for treating Parki...